Thermo Fisher Scientific Sr. Scientist, Group Supervisor, Downstream Process Development in St. Louis, Missouri

Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals.

How will you make an impact?

Directly supervises a small team of scientists that are typically assigned to a specific functional area. Acts as lead on multiple programs. Investigates, creates, and validates new scientific methodologies on a complex scope of projects. Works on technical/scientific project activities to execute strategies and technical solutions that meet client needs and expectations. Leads technical discussions with clients with a high level of technical proficiency. Evaluates and oversees the design of processes and supports problem solving. Makes decisions that require developing new options to solve complex problems. Determines methods and procedures on new assignments and may coordinate activities of other employees.

What will you do?

  • Provides leadership to assigned staff by performing the following: leading organizational change; developingand empowering staff; cultivating relationships; putting staff in a position to succeed, meeting their personalcareer goals while also achieving organizational goals; building effective teams that apply their diverse skillsand perspectives to achieve common goals; driving engagement and creating a climate where staff aremotivated to do their best. Leads design of experimental plans based on the defined deliverables.

  • Conducts complex analyses to support process development. Works with Process Development and Manufacture groups to trouble-shoot process challenges.

  • Records results in notebook accurately, clearly, and regularly, and reviews documentation by others.

  • Prepares protocols, reports, and test methods and writes SOPs.

  • Maintains and ensures safe laboratory environment and work practices.

  • Executes appropriately record and evaluate experimental data, including the writing and revising of process development reports and technology transfer protocols as needed.

  • Remains current in the field by review of relevant scientific literature and attendance at appropriate scientific seminars and conferences.

  • Leads development of recombinant protein purification processes, including chromatography process, ultrafiltration / diafiltration, nanofiltration, process characterization and optimization, process scale up, scale down model qualification, viral clearance validation. Leads development of transfer of purification processes which can be scaled up for protein production and facilitates the Technology Transfer to Downstream Manufacturing group.

How will you get here?

Education/Experience:

  • Bachelor's degree or Master’s degree or PhD in biology, chemistry, biochemistry, chemical engineering, or a related field.

  • With Bachelor’s degree, minimum of 8 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory and that includes relevant industry and discipline experience.

  • With Master’s degree, 6 years of experience related to pharmaceutical manufacturing, process, development or academic laboratory and that includes at least 2 years of relevant industry discipline experience.

  • With PhD, significant practical scientific application directly related to job responsibilities; related industry and discipline experience preferred.

Knowledge, Skills, Abilities:

  • Advanced and deep knowledge of varied aspects or a specialized aspect of discipline and working knowledge of principles and concepts in other relevant disciplines.

  • Exceptional knowledge of general cGLP procedures and those specific to discipline.

  • Strong knowledge of GMP/ GLP regulations in cGMP/ cGLP manufacturing environment. Demonstrated leadership skills.

  • Excellent problem solving and critical thinking skills.

  • Outstanding writing, communication and presentation skills. Must be able to speak effectively before groups of customers and employees. Ability to make and communicate complex decisions.

  • Strong MS Excel, PowerPoint and Word skills. Microsoft Project skills preferred.

  • Excellent organization and planning skills. Strong attention to detail and ability to adhere to standards procedures.

  • Design complex studies based on the deliverables.

  • Analyze and summarize complex scientific data. Author reports, procedures, and other documents.

  • Able to function in a rapidly changing environment. Strong attention to detail and ability to adhere to standards procedures.

  • Ability to read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.

  • Apply complex mathematical concepts to physical problems in areas.

  • Ability to apply rigorous attention to detail when executing experimental protocols.

  • Perform all process steps and to guide manufacturing on the operation of all process steps.

  • Ability to apply complex mathematical concepts to physical problems in areas such as heat and mass transport.

  • Lead and mentor less experienced staff.

Physical Requirements:

  • Position requires ordinary ambulatory skills and physical coordination sufficient to move about office locations; ability to stand, walk, stoop, kneel, crouch periodically for prolonged periods of time; manipulation (lift, carry, move) of light to medium weights of 10-35 pound pounds; arm, hand and finger dexterity, including ability to grasp and type for prolonged periods of time; visual acuity to use a keyboard, computer monitor, operate equipment, and read materials for prolonged periods of time; ability to sit, reach with hands and arms, talk, and hear for prolonged periods of time.

  • Lift objects up to 50 lbs. occasionally.

  • Stand up to 20% daily.

  • Walk within lab and between buildings daily.

  • Repetitive hand motions.

At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

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Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.