Pfizer Associate Scientist, Formulation Development in St. Louis, Missouri
Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
As an Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. This position will be part of Pharmaceutical Research and Development organization. The colleague will participate in the formulation and process development, scale-up and transfer of protein therapeutics formulations and manufacturing processes. This position will be responsible for performing analytical characterization of candidate molecules by using various biophysical and biochemical characterization techniques.
This is a laboratory based position performing formulation and process development activities specifically for biotherapeutics candidates from pre-clinical and Ph I clinical trials through manufacturing process performance qualification, license application and commercialization. Furthermore this position will assist in developing processes for drug product manufacturing, responsible for data compilation, data presentations and report writing.
It is your dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.
How You Will Achieve It
The responsibilities of the Associate Scientist position include, but are not limited to:
Participating in developing parenteral formulations for biotherapeutic modalities such as monoclonal antibodies, antibody drug conjugates, proteins and vaccines.
Participating in developing and defining novel formulations for protein therapeutics products.
Assist in developing manufacturing processes, under general supervision
Perform rapid, comprehensive characterization of candidate molecules to determine the stability profile and applying this information to develop an appropriate dosage form to meet clinical needs. This will be achieved by applying various biophysical and biochemical techniques such as HPLC (SE-HPLC, IEX, RP-HPLC), SDS-PAGE, Capillary Gel electrophoresis (CGE), and imaged Capillary Electrophoresis (iCE).
Assist in the development and scale-up of processes from bench top to pilot scale and, as required, technology transfer to commercial plants.
Preparing data summary presentation, compiling data and authoring technical reports.
Interact effectively with a multi-disciplinary team of scientists for formulation optimization and overall candidate progression
Bachelor's Degree in a relevant discipline
0-3 years of experience in Pharmaceutics, Chemistry, Chemical/Biochemical Engineering, Pharmacy , Biology, B iochemistry, Biotechnology
Working knowledge of formulation and process considerations for biotherapeutics including cell and gene therapy, vaccines, monoclonal antibodies, etc
Demonstrated experience delivering high quality and timely data while adhering to compliance and data integrity requirements
Accelerant learner and demonstrated team player, able to take direction from supervisors and project leads,
Actively contributes to and supports a positive work environment
Organizes, performs and documents high quality and timely lab work
Communicates well in written form and verbally in tech teams
Demonstrates curiosity and takes initiative in learning the business and opportunities for professional growth
Other Job Details
Eligible for Employee Referral Bonus
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Research and Development